In 1995, the Santosh Medical/Dental Colleges and Hospitals came up as one of the top institutions in India to study medicine in Ghaziabad. The university has been offering an MBBS course since 1996 with a total intake of around 50 students per year. 2005 onwards, the course was recognised by the Ministry of Health and Family Welfare of the Government of India and the capacity of accepting a particular number of admissions was increased to 100. 20 years after its inception, the institute is considered as the best medical university, India.

In the same manner, Santosh Dental College started in 1995 with an aim of imparting a higher level education in dentistry. The institution offers a foundation course in BDS since 1996 by accepting about 40 students annually. But the number of admissions went up higher to 100 per year after 2005. It has now become the best university for higher education.

Santosh Deemed to be University is established in a sprawling area of about varietal landscape in Ghaziabad(Delhi NCR). It is run by "SANTOSH TRUST", managed by service minded philanthropists for whom virtue is not a goal but is way of life.

The Trust, managed by like-minded eminent personalities, who relentlessly endeavour to achieve excellence in every field they enter into, has the ever growing spirit to put the Institution in the Global Map of Medical Academy, through sheer commitment to service of mankind. Hence, it is no wonder that the Trust has entrusted the development of every one of the following institutions to experienced and enterprising experts in the respective sector with the main objective of achieving-state-of-the art standards, under the dynamic leadership of Dr. P. Mahalingam, M.D. (General medicine). DM (Cardiology). FCCP, an eminent Cardiologist and Educationist of International repute, who is the Chairman and Dr Santosh Mahalingam, Vice –Chairman both are Managing Trustee of the Trust, The guiding force behind this entire Mega project of Santosh Deemed to be University.